Neural Tube Defects

We do not routinely see patients with an isolated neural tube defect in the Genetics service. However, if there are additional features which might suggest an underlying genetic syndrome, or a family history of close relatives who are affected with a neural tube defect, then referral to Clinical Genetics may be appropriate.

Women who have had a previous pregnancy affected by a neural tube defect, or have a family history of a neural tube defect, are advised to take high dose folic acid (5mg), which can be prescribed by their GP. This can significantly reduce the chance of having another baby with a neural tube defect.